Le Quoc Minh started his journalism career in 1990. He worked as a world news editor at the Vietnam News Agency (VNA), the only wire news service in the country, before his four-year stay in Japan as an expert in humanities for the Radio Japan, NHK World. Coming back early 2000, Minh was a senior editor for VNA's news department for foreign service where he developed a news website for the agency. He became acting director of the department since June 2008 and at the same time editor-in-chief of VietnamPlus at www.vietnamplus.vn which delivers news about Vietnam and the world in five languages

– Vietnamese, English, French, Spanish and Chinese. Minh was promoted to Vice President of the Vietnam News Agency in November 2017.

He is the person behind VNA's various innovative journalism projects include RapNewsPlus which deliver news in rap music to young audience, video 360 degrees, chatbot, paywall, drone journalism, data journalism, long-form stories, newsgame and pioneering infographics project which he started in 2004. The RapNewsPlus won the top award in 2014 in the Digital First category of the World Young Reader Prizes, the annual awards from the World Association of Newspapers and News Publishers (WAN-IFRA) that honor excellence in newspaper engagement of the young.